Article
Pharmacogenetics of lithium effects on glomerular function in bipolar disorder patients under chronic lithium treatment: a pilot study.
Neuroscience letters - 18 Jan 2017
Tsermpini Evangelia Eirini, Zhang Yanfei, Niola Paola, Chillotti Caterina, Ardau Raffaella, Bocchetta Alberto, Patrinos George P, Del Zompo Maria, Severino Giovanni, Lee Ming Ta Michael, Squassina Alessio
Abstract excerpt
Bipolar disorder (BD) is a psychiatric disease characterized by alternating episodes of mania and depression. Lithium (Li) represents the mainstay treatment for BD, although a significant proportion of patients shows insufficient or no response. Li is also associated with potentially severe side effects, including renal effects. Several studies reported that Li may induce reduction of glomerular filtration rate...
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