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Article

Mutational analysis of the transforming growth factor beta receptor type I gene in primary non-small cell lung cancer.

Lung cancer (Amsterdam, Netherlands) - 1 Jun 2003

Zhang Hong-Tao, Fei Qing-Yan, Chen Feng, Qi Qing-Yuan, Zou Wei, Wang Jiu-Cun, Zhang Rong-Mei, Tao Shi-Heng, Chen Xiao-Feng, Luo Ze-Wei

Abstract excerpt

Transforming growth factor-beta receptor-dependent signals are critical for cell growth and differentiation and are often disrupted during tumorigenesis. The entire coding region of TGFbetaRI and flanking intron sequences from 53 primary non-small cell lung cancer (NSCLC) tissues were examined for alterations using SSCP and direct sequencing. No somatic point mutations other than two silent mutations and a...

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PMID: 12781426
DOI: 10.1016/s0169-5002(03)00121-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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