Article
Association of the transforming growth factor ß1 promoter polymorphism, C-509T, with smoking status and survival in advanced non-small cell lung cancer.
Oncology reports - 1 Feb 2011
Togashi Yosuke, Masago Katsuhiro, Fujita Shiro, Kim Young Hak, Sakamori Yuichi, Hatachi Yukimasa, Fukuhara Akiko, Nagai Hiroki, Mio Tadashi, Mishima Michiaki
Abstract excerpt
Transforming growth factor ß (TGF-ß) signaling can inhibit tumor growth in developing tumors. However, it promotes tumor invasiveness and metastasis in late-stage tumors. A number of TGF-ß gene polymorphisms have been identified that can affect the survival of patients with advanced non-small cel...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
