Article

Genetic mutation of transforming growth factor beta type II receptor in oral squamous cell carcinoma

2009-08-11

Abstract excerpt

ABSTRACT Background and aim: The deregulation of transforming growth factor β ( TGF‐β ) action and its signaling function has been a widely accepted concept in carcinogenesis. However, its dual roles, as a tumor suppressor gene and oncogene, have interfered in applying TGF‐β signaling to cancer therapeutics. To evaluate its role in the carcinogenesis of oral squamous cell carcinoma (OSCC), we performed mutational...

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Literature Corpus work: 11586369-2fb2-5aa0-8926-97979f4bf273
DOI: 10.1111/j.1755-9294.2009.01046.x

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