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Article

P53 (codon 72) and P21 (codon 31) polymorphisms alter in vivo mRNA expression of p21.

Lung cancer (Amsterdam, Netherlands) - 1 Jun 2003

Su Li, Sai Yang, Fan Rong, Thurston Sally W, Miller David P, Zhou Wei, Wain John C, Lynch Thomas J, Liu Geoffrey, Christiani David C

Abstract excerpt

p21 (Waf1/Cip1) is a downstream target of p53. We evaluated the association between p21 polymorphism (codon 31), p53 polymorphism (codon 72) and their corresponding in vivo mRNA expression. In this study, p21 and p53 genetic polymorphisms (using standard PCR-RFLP techniques) and p21 and p53 gene expressions (using a radiolabelled ribonuclease protection assay (RPA) technique) were evaluated in the peripheral...

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PMID: 12781424
DOI: 10.1016/s0169-5002(03)00081-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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