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Article

Polymorphisms of p53 and p21 genes in chronic obstructive pulmonary disease.

The Journal of laboratory and clinical medicine - 1 May 2006

Lee Yao-Ling, Chen Wei, Tsai Wen-Kai, Lee Jen-Chih, Chiou Hui-Ling, Shih Chuen-Ming, Wang Yi-Ching

Abstract excerpt

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a multifactorial disease influenced by genetic and environmental factors, particularly cigarette smoking. Although cigarette smoke may be directly mutagenic, polymorphisms in the genes controlling acquired somatic mutations may also contribute, at least to some extent, to the observed differing susceptibilities to COPD. To investigate the involvement of...

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Identifiers

PMID: 16697770
DOI: 10.1016/j.lab.2005.12.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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