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Article

p53 and p21 genetic polymorphisms and susceptibility to endometrial cancer.

Gynecologic oncology - 1 May 2004

Roh Ju Won, Kim Jae Weon, Park Noh Hyun, Song Yong Sang, Park In Ae, Park Sang-Yoon, Kang Soon Beom, Lee Hyo Pyo

Abstract excerpt

OBJECTIVE: Recently, there has been considerable interest in the association of specific cancers with single nucleotide polymorphisms (SNPs). In this regard, genetic polymorphism at codon 72 (CCC/proline to CGC/arginine [Pro(72)Arg]) of the p53 gene is one of the most frequently studied subjects. An association between endometrial cancer and the polymorphism at codon 31 (AGC/serine to AGA/arginine [Ser(31)Arg])...

Topics

Adult
Alleles
Case-Control Studies
Cyclin-Dependent Kinase Inhibitor p21
Cyclins
Endometrial Neoplasms
Female
Genes, p53
Genetic Predisposition to Disease
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Polymerase Chain Reaction

Polymorphism, Single Nucleotide

Risk Factors

Source

Identifiers

PMID: 15099969
DOI: 10.1016/j.ygyno.2004.02.005

Genes

AGA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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