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Article

Interleukin 1 genotypes in multiple sclerosis and relationship to disease severity.

Journal of neuroimmunology - 1 Aug 2002

Mann C L A, Davies M B, Stevenson V L, Leary S M, Boggild M D, Ko Ko C, Jones P W, Fryer A A, Strange R C, Thompson A J, Hawkins C P

Abstract excerpt

We studied the association between clinical outcome in MS and allelic variants single nucleotide polymorphisms (SNPs) of interleukin-1alpha (IL-1alpha), IL-1beta and a variable number tandem repeat (VNTR) in IL-1 receptor antagonist (IL-1RN). A total of 377 patients with MS were studied. Significant associations between IL-1 genotypes and clinical outcome were found using logistic regression after correction for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12161036
DOI: 10.1016/s0165-5728(02)00181-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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