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Article

IL-1 receptor antagonist (IL-1RA) gene polymorphism in Sjögren's syndrome and rheumatoid arthritis.

Clinical immunology and immunopathology - 1 Jun 1998

Perrier S, Coussediere C, Dubost J J, Albuisson E, Sauvezie B

Abstract excerpt

The gene encoding interleukin-1 receptor antagonist (IL-1ra) has a variable allelic polymorphism. The IL1RN*2 allele was recently described as a factor of severity in several autoimmune diseases and was paradoxically associated with increased production of IL-1ra by monocytes in vitro. We studied...

Topics

Alleles
Arthritis, Rheumatoid
C-Reactive Protein
Humans
Interleukin 1 Receptor Antagonist Protein
Interleukin-1
Polymorphism, Genetic
Sialoglycoproteins
Sjogren's Syndrome
Transforming Growth Factor beta
Tumor Necrosis Factor-alpha

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9646842
DOI: 10.1006/clin.1998.4520

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CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9646842-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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