Article
IL-2, IFN-gamma, and IL-12 gene polymorphisms and susceptibility to multiple sclerosis.
Journal of clinical immunology - 1 Nov 2009
Shokrgozar Mohammad Ali, Sarial Sheila, Amirzargar Aliakbar, Shokri Fazel, Rezaei Nima, Arjang Zohreh, Radfar Jalaledin, Yousefi-Behzadi Manijeh, Ali Sahraian Mohammad, Lotfi Jamshid
Abstract excerpt
BACKGROUND: Multiple sclerosis (MS) is a multifactorial disease. Positive genetic background could predispose individuals to this chronic disabling disease. In order to investigate the role of some proinflammatory cytokines (interleukin (IL)-2, IL-12, and interferon-gamma (IFN-gamma)) as a risk factor for MS, this study was performed. METHODS: Two hundred and eleven patients with relapsing-remitting form of MS...
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