Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of interleukin-1beta and interleukin-1 receptor antagonist genes with disease severity in MS.

Neurology - 1 Feb 1999

Schrijver H M, Crusius J B, Uitdehaag B M, García González M A, Kostense P J, Polman C H, Peña A S

Abstract excerpt

OBJECTIVE: To investigate whether polymorphisms in the interleukin (IL)-1beta and IL-1 receptor antagonist (IL-1RA) genes are associated with both susceptibility to and clinical characteristics of MS. BACKGROUND: Genetic susceptibility to MS is determined by many partially identified genes. The genes encoding various cytokines are logical candidates for MS susceptibility and phenotype. METHODS: Genotypes were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Interleukin-1
Share to Multiple Sclerosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Polymorphism, Genetic

Share to Receptors, Interleukin-1

Source

Identifiers

PMID: 10025794
DOI: 10.1212/wnl.52.3.595

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of interleukin-1beta and interleukin-1 receptor antagonist genes with disease severity in MS.PMID 10025794Read ↗

Interleukin (IL)-1 gene polymorphisms: relevance of disease severity associated alleles with IL-1beta and IL-1ra production in multiple sclerosis.Semantic proximity Read ↗

Association of two variants in IL-1beta and IL-1 receptor antagonist genes with multiple sclerosis.Semantic proximity Read ↗

A study of interleukin-1 cluster genes in susceptibility to and severity of multiple sclerosis.Semantic proximity Read ↗

Interleukin 1 genotypes in multiple sclerosis and relationship to disease severity.Semantic proximity Read ↗

Genetic polymorphisms of IL-1beta and IL-1 receptor antagonist in association with multiple sclerosis in Japanese patients.Semantic proximity Read ↗

Relevance of interleukin 1 receptor antagonist intron 2 polymorphism in Italian MS patients.Semantic proximity Read ↗

Genetic variants in IL2RA and IL7R affect multiple sclerosis disease risk and progression.Semantic proximity Read ↗

The interleukin-1 gene family in multiple sclerosis susceptibility and disease course.Semantic proximity Read ↗

Association of interleukin-1 gene cluster polymorphisms and haplotypes with multiple sclerosis in an Iranian population.Semantic proximity Read ↗

[Association analysis of cytokine receptors' genes polymorphisms with clinical features of multiple sclerosis].Semantic proximity Read ↗

IL-1 polymorphisms modulates functional recovery following rehabilitation in multiple sclerosis.Semantic proximity Read ↗

Circulating Interleukins and Risk of Multiple Sclerosis: A Mendelian Randomization Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.