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Article

UVA-induced cyclobutane pyrimidine dimers form predominantly at thymine-thymine dipyrimidines and correlate with the mutation spectrum in rodent cells.

Nucleic acids research - 1 Jun 2003

Rochette Patrick J, Therrien Jean-Philippe, Drouin Régen, Perdiz Daniel, Bastien Nathalie, Drobetsky Elliot A, Sage Evelyne

Abstract excerpt

Ligation-mediated PCR was employed to quantify cyclobutane pyrimidine dimer (CPD) formation at nucleotide resolution along exon 2 of the adenine phosphoribosyltransferase (aprt) locus in Chinese hamster ovary (CHO) cells following irradiation with either UVA (340-400 nm), UVB (295-320 nm), UVC (254 nm) or simulated sunlight (SSL; lambda > 295 nm). The resulting DNA damage spectrum for each wavelength region was...

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Identifiers

PMID: 12771205
DOI: 10.1093/nar/gkg402
PMCID: PMC156735

Genes

CPD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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