Article
The mutational specificity of simulated sunlight at the aprt locus in rodent cells.
Carcinogenesis - 1 Aug 1994
Drobetsky E A, Moustacchi E, Glickman B W, Sage E
Abstract excerpt
To elucidate the nature of sunlight mutagenesis in mammalian cells, the mutational specificity of simulated solar light (SSL) has been established at the Chinese hamster ovary adenine phosphoribosyltransferase (aprt) locus. Among a collection of 36 independent SSL-induced mutations, the majority were single or tandem double C-->T transitions at dipyrimidine sites. This is consistent with previous investigations...
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