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Article

Scanning the cystic fibrosis transmembrane conductance regulator gene using high-resolution DNA melting analysis.

Clinical chemistry - 1 Nov 2007

Montgomery Jesse, Wittwer Carl T, Kent Jana O, Zhou Luming

Abstract excerpt

BACKGROUND: Complete gene analysis of the cystic fibrosis transmembrane conductance regulator gene (CFTR) by scanning and/or sequencing is seldom performed because of the cost, time, and labor involved. High-resolution DNA melting analysis is a rapid, closed-tube alternative for gene scanning and genotyping. METHODS: The 27 exons of CFTR were amplified in 37 PCR products under identical conditions. Common...

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Source

Identifiers

PMID: 17890437
DOI: 10.1373/clinchem.2007.092361

Genes

CFTR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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