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Article

NMDA receptor trafficking through an interaction between PDZ proteins and the exocyst complex.

Nature cell biology - 1 Jun 2003

Sans Nathalie, Prybylowski Kate, Petralia Ronald S, Chang Kai, Wang Ya-Xian, Racca Claudia, Vicini Stefano, Wenthold Robert J

Abstract excerpt

NMDA (N-methyl-D-aspartate) receptors (NMDARs) are targeted to dendrites and anchored at the post-synaptic density (PSD) through interactions with PDZ proteins. However, little is known about how these receptors are sorted from the endoplasmic reticulum and Golgi apparatus to the synapse. Here, we find that synapse-associated protein 102 (SAP102) interacts with the PDZ-binding domain of Sec8, a member of the...

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Source

Identifiers

PMID: 12738960
DOI: 10.1038/ncb990

Genes

PSD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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