Article
Cell surface expression of GluR5 kainate receptors is regulated by an endoplasmic reticulum retention signal.
The Journal of biological chemistry - 26 Dec 2003
Ren Zhao, Riley Nathan J, Needleman Leigh A, Sanders James M, Swanson Geoffrey T, Marshall John
Abstract excerpt
Kainate receptors (KARs) are mediators of excitatory neurotransmission in the mammalian central nervous system, and their efficient targeting and trafficking is critical for normal synaptic function. A key step in the delivery of KARs to the neuronal plasma membrane is the exit of newly assembled receptors from the endoplasmic reticulum (ER). Here we report the identification of a novel ER retention signal in the...
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