Article
A new motif necessary and sufficient for stable localization of the delta2 glutamate receptors at postsynaptic spines.
The Journal of biological chemistry - 23 Jun 2006
Matsuda Shinji, Matsuda Keiko, Yuzaki Michisuke
Abstract excerpt
The number of each subclass of ionotropic glutamate receptors (iGluRs) at the spines is differentially regulated either constitutively or in a neuronal activity-dependent manner. The delta2 glutamate receptor (GluRdelta2) is abundantly expressed at the spines of Purkinje cell dendrites and controls synaptic plasticity in the cerebellum. To obtain clues to the trafficking mechanism of the iGluRs, we expressed...
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