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Article

Association of a missense mutation in the NOS3 gene with exhaled nitric oxide levels.

American journal of respiratory and critical care medicine - 15 Jul 2003

Storm van's Gravesande Karin, Wechsler Michael E, Grasemann Hartmut, Silverman Eric S, Le Louis, Palmer Lyle J, Drazen Jeffrey M

Abstract excerpt

There is evidence that genetic factors affect nitric oxide formation and that sequence variants in the nitric oxide synthase genes contribute to the observed variance of nitric oxide levels in exhaled air (fraction of expired nitric oxide, FENO) in subjects with asthma. We identified a strong association between a known functional NOS3 missense sequence variant in the endothelial nitric oxide gene (G894T) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12738608
DOI: 10.1164/rccm.200212-1491BC

Genes

NOS3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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