Article
Environmental exposures, nitric oxide synthase genes, and exhaled nitric oxide in asthmatic children.
Pediatric pulmonology - 1 Aug 2009
Spanier Adam J, Kahn Robert S, Hornung Richard W, Wang Ning, Sun Guangyun, Lierl Michelle B, Lanphear Bruce P
Abstract excerpt
Exhaled nitric oxide (FeNO), a measure of airway inflammation, is being explored as a tool to guide asthma management in children. Investigators have identified associations of genetic polymorphisms in nitric oxide synthase genes (NOS1 and NOS3) with FeNO levels; however, none have explored whether these polymorphisms modify the relationship of environmental exposures with FeNO. The objective of this project was...
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