Article
Exhaled nitric oxide in patients with asthma: association with NOS1 genotype.
American journal of respiratory and critical care medicine - 1 Dec 2000
Wechsler M E, Grasemann H, Deykin A, Silverman E K, Yandava C N, Israel E, Wand M, Drazen J M
Abstract excerpt
An increased concentration of nitric oxide (NO) in exhaled air (FENO) is now recognized as a critical component of the asthmatic phenotype. When we identified patients with asthma on the basis of a standard case definition alone, we found that they were remarkably heterogeneous with respect to their FENO. However, when we included genotype at a prominent asthma candidate gene (i.e., NOS1) in the case definition,...
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