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Article

Functional characterization in yeast of genetic variants in the human equilibrative nucleoside transporter, ENT1.

Pharmacogenetics - 1 May 2003

Osato Douglas H, Huang Conrad C, Kawamoto Michiko, Johns Susan J, Stryke Doug, Wang Joanne, Ferrin Thomas E, Herskowitz Ira, Giacomini Kathleen M

Abstract excerpt

The human equilibrative nucleoside transporter, ENT1, appears to play a critical role in the disposition of nucleosides and nucleoside analogs used clinically as anti-viral and anti-cancer drugs. Recently, we identified variants of ENT1 in an ethnically diverse DNA sample set from 247 individuals, focusing primarily on the coding region. The goal of the present study was to analyse the haplotype structure and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 12724623
DOI: 10.1097/00008571-200305000-00010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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