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Article

Targeting the Plasmodium vivax equilibrative nucleoside transporter 1 (PvENT1) for antimalarial drug development.

International journal for parasitology. Drugs and drug resistance - 1 Apr 2016

Deniskin Roman, Frame I J, Sosa Yvett, Akabas Myles H

Abstract excerpt

Infection with Plasmodium falciparum and vivax cause most cases of malaria. Emerging resistance to current antimalarial medications makes new drug development imperative. Ideally a new antimalarial drug should treat both falciparum and vivax malaria. Because malaria parasites are purine auxotrophic, they rely on purines imported from the host erythrocyte via Equilibrative Nucleoside Transporters (ENTs). Thus, the...

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Identifiers

PMID: 26862473
DOI: 10.1016/j.ijpddr.2015.11.003
PMCID: PMC4706624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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