Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional role of the polymorphic 647 T/C variant of ENT1 (SLC29A1) and its association with alcohol withdrawal seizures.

PloS one - 24 Jan 2011

Kim Jeong-Hyun, Karpyak Victor M, Biernacka Joanna M, Nam Hyung Wook, Lee Moonnoh R, Preuss Ulrich W, Zill Peter, Yoon Gihyun, Colby Colin, Mrazek David A, Choi Doo-Sup

Abstract excerpt

BACKGROUND: Adenosine is involved in several neurological and behavioral disorders including alcoholism. In cultured cell and animal studies, type 1 equilibrative nucleoside transporter (ENT1, slc29a1), which regulates adenosine levels, is known to regulate ethanol sensitivity and preference. Int...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcoholism
Share to Cell Line
Share to DNA, Complementary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Knockout

Share to Mice, Mutant Strains

Share to Polymorphism, Single Nucleotide

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 21283641
DOI: 10.1371/journal.pone.0016331
PMCID: PMC3026043

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21283641-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional role of the polymorphic 647 T/C variant of ENT1 (SLC29A1) and its association with alcohol withdrawal seizures.PMID 21283641Read ↗

The type 1 equilibrative nucleoside transporter regulates ethanol intoxication and preference.Semantic proximity Read ↗

Functional characterization in yeast of genetic variants in the human equilibrative nucleoside transporter, ENT1.Semantic proximity Read ↗

Equilibrative nucleotide transporter ENT3 (SLC29A3): A unique transporter for inherited disorders and cancers.Semantic proximity Read ↗

A Comprehensive Functional Assessment of Carboxylesterase 1 Nonsynonymous Polymorphisms.Semantic proximity Read ↗

Functional characterization and haplotype analysis of polymorphisms in the human equilibrative nucleoside transporter, ENT2.Semantic proximity Read ↗

Pharmacogenetic Effects of Naltrexone in Individuals of East Asian Descent: Human Laboratory Findings from a Randomized Trial.Semantic proximity Read ↗

Functional effects of protein sequence polymorphisms in the organic cation/ergothioneine transporter OCTN1 (SLC22A4)Semantic proximity Read ↗

SLC19A1 Genetic Variation Leads to Altered Thiamine Diphosphate Transport: Implications for the Risk of Developing Wernicke-Korsakoff's Syndrome.Semantic proximity Read ↗

Genetic variation of the glutamate transporter EAAT2 gene and vulnerability to alcohol dependence.Semantic proximity Read ↗

Commentary on Efficacy and Safety of Low dose ondansetron as a prospective precision medicine to treat alcohol use disorder phenotypes.Semantic proximity Read ↗

Mutation of the inhibitory ethanol site in GABAA ρ1 receptors promotes tolerance to ethanol-induced motor incoordination.Semantic proximity Read ↗

Interaction of SLC6A4 and DRD2 polymorphisms is associated with a history of delirium tremens.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.