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Article

The NB protein of influenza B virus is not necessary for virus replication in vitro.

Journal of virology - 1 May 2003

Hatta Masato, Kawaoka Yoshihiro

Abstract excerpt

The NB protein of influenza B virus is thought to function as an ion channel and therefore would be expected to have an essential function in viral replication. Because direct evidence for its absolute requirement in the viral life cycle is lacking, we generated NB knockout viruses by reverse genetics and tested their growth properties both in vitro and in vivo. Mutants not expressing NB replicated as efficiently...

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Identifiers

PMID: 12719596
DOI: 10.1128/jvi.77.10.6050-6054.2003
PMCID: PMC154028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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