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Article

Most Influenza A Virions Fail To Express at Least One Essential Viral Protein

3 Jan 2013

Abstract excerpt

Segmentation of the influenza A virus (IAV) genome enables rapid gene reassortment at the cost of complicating the task of assembling the full viral genome. By simultaneously probing for the expression of multiple viral proteins in MDCK cells infected at a low multiplicity with IAV, we observe that the majority of infected cells lack detectable expression of one or more essential viral proteins. Consistent with...

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PMID: 23283949
DOI: 10.1128/jvi.02284-12

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