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Article

Influenza type A virus neuraminidase does not play a role in viral entry, replication, assembly, or budding.

Journal of virology - 1 Feb 1995

Liu C, Eichelberger M C, Compans R W, Air G M

Abstract excerpt

We have used a neuraminidase-deficient influenza virus, NWS-Mvi, which was selected by supplying bacterial neuraminidase in the medium (C. Liu and G. M. Air, Virology 194:403-407, 1993), to define the role of neuraminidase in influenza virus replication. Electron microscopy showed that virions of the NWS-Mvi mutant assembled normally and formed large aggregates associated with cell surfaces. The NWS-Mvi virus...

Topics

Animals
Cell Line
Dogs
Endocytosis
Female
Influenza A virus
Mice
Mice, Inbred C57BL
Mutation
Neuraminidase
Virus Replication

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Identifiers

PMID: 7815489
DOI: 10.1128/JVI.69.2.1099-1106.1995
PMCID: PMC188682

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7815489-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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