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Article

Reduced levels of neuraminidase of influenza A viruses correlate with attenuated phenotypes in mice.

The Journal of general virology - 1 Mar 2000

Solorzano A, Zheng H, Fodor E, Brownlee G G, Palese P, García-Sastre A

Abstract excerpt

We have previously obtained four transfectant influenza A viruses containing neuraminidase (NA) genes with mutated base pairs in the conserved double-stranded RNA region of the viral promoter by using a ribonucleoprotein transfection system. Two mutant viruses (D2 and D1/2) which share a C-G-->A-U mutation at positions 11 and 12 of the 3' and 5' ends, respectively, of the NA gene, showed an approximate 10-fold...

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Source

Identifiers

PMID: 10675411
DOI: 10.1099/0022-1317-81-3-737

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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