Article
A model of the nuclear control of mitochondrial DNA replication.
Journal of theoretical biology - 21 Apr 2003
Capps Graham J, Samuels David C, Chinnery Patrick F
Abstract excerpt
Mitochondria are the semi-autonomous organelles that are responsible for generating the majority of the energy required by mammalian cells under normal conditions. They are only semi-autonomous because the replication, transcription and translation of the DNA molecules within the mitochondrion, mtDNA, are ultimately controlled by the cell nucleus. We present a series of three models of the nuclear control of...
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