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Article

Genetic variability in MCF-7 sublines: evidence of rapid genomic and RNA expression profile modifications.

BMC cancer - 24 Apr 2003

Nugoli Mélanie, Chuchana Paul, Vendrell Julie, Orsetti Béatrice, Ursule Lisa, Nguyen Catherine, Birnbaum Daniel, Douzery Emmanuel J P, Cohen Pascale, Theillet Charles

Abstract excerpt

BACKGROUND: Both phenotypic and cytogenetic variability have been reported for clones of breast carcinoma cell lines but have not been comprehensively studied. Despite this, cell lines such as MCF-7 cells are extensively used as model systems. METHODS: In this work we documented, using CGH and RNA expression profiles, the genetic variability at the genomic and RNA expression levels of MCF-7 cells of different...

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Identifiers

PMID: 12713671
DOI: 10.1186/1471-2407-3-13
PMCID: PMC156633

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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