Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Different coexisting genotypes in the breast cancer cell line MDA-MB-468].

Der Pathologe - 1 Nov 2008

Agelopoulos K, Schmidt H, Korsching E, Buerger H, Brandt B

Abstract excerpt

Intratumor genetic heterogeneity, a well-known characteristic of numerous cancers, often confounds a precise diagnosis and leads to therapy resistance. This study deals with such chromosomal variability, which may be due to an inherent genetic instability affecting heterogeneity and clonal effects. Subpopulations of the breast cancer cell line MDA-MB-468 were isolated according to epidermal growth factor receptor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Chromosomal Instability
Share to Chromosome Fragile Sites

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to ErbB Receptors

Share to Gene Amplification

Share to Gene Expression Regulation, Neoplastic

Share to Genetic Heterogeneity

Share to In Situ Hybridization, Fluorescence

Source

Identifiers

PMID: 18751981
DOI: 10.1007/s00292-008-1021-3

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Different coexisting genotypes in the breast cancer cell line MDA-MB-468].PMID 18751981Read ↗

[Tumour genomics: an unstable landscape].Semantic proximity Read ↗

Selective regain of egfr gene copies in CD44+/CD24-/low breast cancer cellular model MDA-MB-468.Semantic proximity Read ↗

Breast cancer intratumor genetic heterogeneity: causes and implications.Semantic proximity Read ↗

Heterogeneity of breast cancer: The importance of interaction between different tumor cell populationsSemantic proximity Read ↗

Molecular Cytogenomic Characterization of the Murine Breast Cancer Cell Lines C-127I, EMT6/P and TA3 HauschkaSemantic proximity Read ↗

Intra-tumour genetic heterogeneity and poor chemoradiotherapy response in cervical cancerSemantic proximity Read ↗

Genetic variability in a frozen batch of MCF-7 cells invisible in routine authentication affecting cell function.Semantic proximity Read ↗

Molecular cytogenetic characterization of human breast cancer cell line MDA-MB-468 and its variant 468LN, which displays aggressive lymphatic metastasis.Semantic proximity Read ↗

<i>HER2</i> genetic heterogeneity in breast carcinomaSemantic proximity Read ↗

Comparative genomic hybridization analysis of breast tumors with predetermined profiles of DNA amplification.Semantic proximity Read ↗

Somatic genetic changes in human breast cancer.Semantic proximity Read ↗

Heterogeneity in breast cancer and the problem of relevance of findings.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.