Hormone resistance, invasiveness, and metastatic potential in breast cancer.

doi:10.1007/BF01833263

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Article

Hormone resistance, invasiveness, and metastatic potential in breast cancer.

Breast cancer research and treatment - 1 Jan 1993

Clarke R, Thompson E W, Leonessa F, Lippman J, McGarvey M, Frandsen T L, Brünner N

Abstract excerpt

Critical phenotypic changes that occur during the progression of breast cancer include the loss of hormone-dependence, acquired resistance to systemic therapies, and increased metastatic potential. We have isolated a series of MCF-7 human breast cancer variants which exhibit hormone-independent g...

Topics

Breast Neoplasms
Carcinoma
Drug Resistance
Estrogen Antagonists
Female
Gene Expression Regulation, Neoplastic
Hormones
Humans
Neoplasm Invasiveness
Neoplasm Metastasis
Neoplasms, Hormone-Dependent
Phenotype

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