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Article

Genetic instability of RBM5/LUCA‐15/H37 in MCF‐7 breast carcinoma sublines may affect susceptibility to apoptosis

25 Mar 2004

Abstract excerpt

The MCF-7 human breast carcinoma cell line is widely used as a model system by breast cancer researchers and cell biologists investigating apoptosis. Since its establishment 30 years ago, from a patient with metastatic breast cancer, the original MCF-7 cell population has undergone genetic drift to such an extent that numerous genetically diverse sublines now exist. For instance, it has been reported that MCF-7...

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PMID: 15338470
DOI: 10.1002/cbf.1106

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