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Article

Selective regain of egfr gene copies in CD44+/CD24-/low breast cancer cellular model MDA-MB-468.

BMC cancer - 3 Mar 2010

Agelopoulos Konstantin, Greve Burkhard, Schmidt Hartmut, Pospisil Heike, Kurtz Stefan, Bartkowiak Kai, Andreas Antje, Wieczorek Marek, Korsching Eberhard, Buerger Horst, Brandt Burkhard

Abstract excerpt

BACKGROUND: Increased transcription of oncogenes like the epidermal growth factor receptor (EGFR) is frequently caused by amplification of the whole gene or at least of regulatory sequences. Aim of this study was to pinpoint mechanistic parameters occurring during egfr copy number gains leading t...

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Source

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Identifiers

PMID: 20199686
DOI: 10.1186/1471-2407-10-78
PMCID: PMC2841141

Genes

EGFR
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20199686-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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