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SNP detection in transforming growth factor-beta1 gene using bacterial magnetic particles.

Biosensors & bioelectronics - 1 May 2003

Ota Hiroyuki, Takeyama Haruko, Nakayama Hideki, Katoh Takahiko, Matsunaga Tadashi

Abstract excerpt

A single nucleotide polymorphism (SNP) within the transforming growth factor-beta1 (TGF-beta1) gene was detected by hybridization-based method using bacterial magnetic particles (BMPs). TGF-beta1 is commonly associated with a single base change resulting in a Leu(10)-->Pro (T(869)-->C) polymorphism and is a genetic marker for susceptibility to osteoporosis. Short (9 bases) and specific probes were designed to...

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PMID: 12706579
DOI: 10.1016/s0956-5663(03)00015-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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