Article
High throughput SNP detection system based on magnetic nanoparticles separation.
Journal of biomedical nanotechnology - 1 Feb 2013
Liu Bin, Jia Yingying, Ma Man, Li Zhiyang, Liu Hongna, Li Song, Deng Yan, Zhang Liming, Lu Zhuoxuan, Wang Wei, He Nongyue
Abstract excerpt
Single-nucleotide polymorphism (SNP) was one-base variations in DNA sequence that can often be helpful to find genes associations for hereditary disease, communicable disease and so on. We developed a high throughput SNP detection system based on magnetic nanoparticles (MNPs) separation and dual-color hybridization or single base extension. This system includes a magnetic separation unit for sample separation,...
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