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Article

A Locked Nucleic Acid Probe Based on Selective Salt-Induced Effect Detects Single Nucleotide Polymorphisms.

BioMed research international - 1 Jan 2015

Zhang Jing, Wu Huizhe, Chen Qiuchen, Zhao Pengfei, Zhao Haishan, Yao Weifan, Wei Minjie

Abstract excerpt

Detection of single based genetic mutation by using oligonucleotide probes is one of the common methods of detecting single nucleotide polymorphisms at known loci. In this paper, we demonstrated a hybridization system which included a buffer solution that produced selective salt-induced effect and a locked nucleic acid modified 12 nt oligonucleotide probe. The hybridization system is suitable for hybridization...

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Identifiers

PMID: 26347880
DOI: 10.1155/2015/391070
PMCID: PMC4548076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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