Article
Single nucleotide polymorphism detection in aldehyde dehydrogenase 2 (ALDH2) gene using bacterial magnetic particles based on dissociation curve analysis.
Biotechnology and bioengineering - 20 Sept 2004
Maruyama Kohei, Takeyama Haruko, Nemoto Etsuo, Tanaka Tsuyoshi, Yoda Kiyoshi, Matsunaga Tadashi
Abstract excerpt
Single nucleotide polymorphism (SNP) detection for aldehyde dehydrogenase 2 (ALDH2) gene based on DNA thermal dissociation curve analysis was successfully demonstrated using an automated system with bacterial magnetic particles (BMPs) by developing a new method for avoiding light scattering caused by nanometer-size particles when using commercially available fluorescent dyes such as FITC, Cy3, and Cy5 as labeling...
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