Article
High-throughput SNP detection based on PCR amplification on magnetic nanoparticles using dual-color hybridization.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009
He Nongyue, Li Song, Liu Hongna
Abstract excerpt
A microarray-based method for detecting single nucleotide polymorphisms (SNPs) using solid-phase polymerase chain reaction (PCR) on magnetic nanoparticles (MNPs) was developed. In this method one primer with a biotin label is captured by streptavidin-coated MNPs (SA-MNPs), and the PCR products ar...
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