Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plc1p is required for proper chromatin structure and activity of the kinetochore in Saccharomyces cerevisiae by facilitating recruitment of the RSC complex.

Molecular genetics and genomics : MGG - 1 May 2009

Desai Parima, Guha Nilanjan, Galdieri Luciano, Hadi Sara, Vancura Ales

Abstract excerpt

High-fidelity chromosome segregation during mitosis requires kinetochores, protein complexes that assemble on centromeric DNA and mediate chromosome attachment to spindle microtubules. In budding yeast, phosphoinositide-specific phospholipase C (Plc1p encoded by PLC1 gene) is important for functi...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin
Share to Chromatin Assembly and Disassembly
Share to DNA, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Fungal

Share to Inositol Phosphates

Share to Kinetochores

Share to Saccharomyces cerevisiae Proteins

Share to Type C Phospholipases

Source

Identifiers

PMID: 19205744
DOI: 10.1007/s00438-009-0427-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19205744-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plc1p is required for proper chromatin structure and activity of the kinetochore in Saccharomyces cerevisiae by facilitating recruitment of the RSC complex.PMID 19205744Read ↗

Genetic evidence for a role of phospholipase C at the budding yeast kinetochore.Semantic proximity Read ↗

A mutation in PLC1, a candidate phosphoinositide-specific phospholipase C gene from Saccharomyces cerevisiae, causes aberrant mitotic chromosome segregation.Semantic proximity Read ↗

The yeast RSC chromatin-remodeling complex is required for kinetochore function in chromosome segregation.Semantic proximity Read ↗

A mutation in NPS1/STH1, an essential gene encoding a component of a novel chromatin-remodeling complex RSC, alters the chromatin structure of Saccharomyces cerevisiae centromeres.Semantic proximity Read ↗

Analysis of kinesin motor function at budding yeast kinetochores.Semantic proximity Read ↗

Polo kinase recruitment via the constitutive centromere-associated network at the kinetochore elevates centromeric RNA.Semantic proximity Read ↗

Chromatin assembly factor I and Hir proteins contribute to building functional kinetochores in S. cerevisiae.Semantic proximity Read ↗

Chl4p and iml3p are two new members of the budding yeast outer kinetochore.Semantic proximity Read ↗

Roles for the conserved spc105p/kre28p complex in kinetochore-microtubule binding and the spindle assembly checkpoint.Semantic proximity Read ↗

Interactions between the kinetochore complex and the protein kinase A pathway in Saccharomyces cerevisiae.Semantic proximity Read ↗

Yeast phospholipase C is required for normal acetyl-CoA homeostasis and global histone acetylation.Semantic proximity Read ↗

NudC is required for Plk1 targeting to the kinetochore and chromosome congression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.