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Article

Transmodulation between phospholipase D and c-Src enhances cell proliferation.

Molecular and cellular biology - 1 May 2003

Ahn Bong-Hyun, Kim Shi Yeon, Kim Eun Hee, Choi Kyeong Sook, Kwon Taeg Kyu, Lee Young Han, Chang Jong-Soo, Kim Myung-Suk, Jo Yang-Hyeok, Min Do Sik

Abstract excerpt

Phospholipase D (PLD) has been implicated in the signal transduction pathways initiated by several mitogenic protein tyrosine kinases. We demonstrate for the first time that most notably PLD2 and to a lesser extent the PLD1 isoform are tyrosine phosphorylated by c-Src tyrosine kinase via direct association. Moreover, epidermal growth factor induced tyrosine phosphorylation of PLD2 and its interaction with c-Src...

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Share to CSK Tyrosine-Protein Kinase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12697812
DOI: 10.1128/MCB.23.9.3103-3115.2003
PMCID: PMC153190

Genes

PLD2
PLD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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