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Article

Functional Regulation of Phospholipase D Expression in Cancer and Inflammation

3 Jul 2014

Abstract excerpt

Phospholipase D (PLD) regulates downstream effectors by generating phosphatidic acid. Growing links of dysregulation of PLD to human disease have spurred interest in therapeutics that target its function. Aberrant PLD expression has been identified in multiple facets of complex pathological states, including cancer and inflammatory diseases. Thus, it is important to understand how the signaling network of PLD...

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PMID: 24990948
DOI: 10.1074/jbc.r114.569822

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