Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A role of p44/42 mitogen-activated protein kinases in formyl-peptide receptor-mediated phospholipase D activity and oxidant production.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jan 2006

Paruch Sylvain, El-Benna Jamel, Djerdjouri Bahia, Marullo Stéfano, Périanin Axel

Abstract excerpt

Phosphatidylcholine-specific phospholipase D (PLD) is a major cellular source of phosphatidic acid and choline, which regulate various physiopathological processes. PLD activation mediated by chemoattractants involves protein phosphorylation. This study provides pharmacological and biochemical evidence of a major role of p44/42 MAP kinases (ERK1/2) in PLD activation induced by the chemotactic peptide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Butadienes
Share to Chemotaxis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mitogen-Activated Protein Kinase 1

Share to Mitogen-Activated Protein Kinase 3

Share to Nitriles

Share to Oxidants

Share to Phospholipase D

Share to Respiratory Burst

Source

Identifiers

PMID: 16253958
DOI: 10.1096/fj.05-3881fje

Genes

PLD2
PLD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A role of p44/42 mitogen-activated protein kinases in formyl-peptide receptor-mediated phospholipase D activity and oxidant production.PMID 16253958Read ↗

Involvement of phospholipase D2 in lysophosphatidate-induced transactivation of platelet-derived growth factor receptor-beta in human bronchial epithelial cells.Semantic proximity Read ↗

Phosphorylation-dependent regulation of phospholipase D2 by protein kinase C delta in rat Pheochromocytoma PC12 cells.Semantic proximity Read ↗

Role of p38 MAP kinase in diperoxovanadate-induced phospholipase D activation in endothelial cells.Semantic proximity Read ↗

Functional Regulation of Phospholipase D Expression in Cancer and InflammationSemantic proximity Read ↗

Transmodulation between phospholipase D and c-Src enhances cell proliferation.Semantic proximity Read ↗

Role of Src kinase in diperoxovanadate-mediated activation of phospholipase D in endothelial cells.Semantic proximity Read ↗

Tyrosine phosphorylation of protein kinase D in the pleckstrin homology domain leads to activation.Semantic proximity Read ↗

Proteomic identification of 14-3-3zeta as a mitogen-activated protein kinase-activated protein kinase 2 substrate: role in dimer formation and ligand binding.Semantic proximity Read ↗

Inhibition of the MEK1/ERK pathway reduces arachidonic acid release independently of cPLA2 phosphorylation and translocation.Semantic proximity Read ↗

GPCR-mediated Activation of PLCγ2 Initiates Dysregulated Recruitment of Neutrophils in Cold-induced Urticaria in PLAID PatientsSemantic proximity Read ↗

Sequential protein kinase C (PKC)-dependent and PKC-independent protein kinase D catalytic activation via Gq-coupled receptors: differential regulation of activation loop Ser(744) and Ser(748) phosphorylation.Semantic proximity Read ↗

The mechanism of cell membrane ruffling relies on a phospholipase D2 (PLD2), Grb2 and Rac2 association.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.