Article
Characterization of the endosomal sorting signal of the cation-dependent mannose 6-phosphate receptor.
The Journal of biological chemistry - 4 Jul 2003
Nair Prashant, Schaub Beat E, Rohrer Jack
Abstract excerpt
Intracellular cycling of the cation-dependent mannose 6-phosphate receptor (CD-MPR) between different compartments is directed by signals localized in its cytoplasmic tail. A di-aromatic motif (Phe18-Trp19 with Trp19 as the key residue) in its cytoplasmic tail is required for the sorting of the receptor from late endosomes back to the Golgi apparatus. However, the cation-independent mannose 6-phosphate receptor...
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