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Article

Charged residues in the C-terminus of the P2Y1 receptor constitute a basolateral-sorting signal.

Journal of cell science - 15 Jul 2010

Wolff Samuel C, Qi Ai-Dong, Harden T Kendall, Nicholas Robert A

Abstract excerpt

The P2Y(1) receptor is localized to the basolateral membrane of polarized Madin-Darby canine kidney (MDCK) cells. In the present study, we identified a 25-residue region within the C-terminal tail (C-tail) of the P2Y(1) receptor that directs basolateral sorting. Deletion of this sorting signal caused redirection of the receptor to the apical membrane, indicating that the region from the N-terminus to...

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Identifiers

PMID: 20592187
DOI: 10.1242/jcs.060723
PMCID: PMC2894661

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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