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Article

Mcm10 mediates the interaction between DNA replication and silencing machineries.

Genetics - 1 Feb 2009

Liachko Ivan, Tye Bik K

Abstract excerpt

The connection between DNA replication and heterochromatic silencing in yeast has been a topic of investigation for >20 years. While early studies showed that silencing requires passage through S phase and implicated several DNA replication factors in silencing, later works showed that silent chromatin could form without DNA replication. In this study we show that members of the replicative helicase (Mcm3 and...

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Identifiers

PMID: 19064704
DOI: 10.1534/genetics.108.099101
PMCID: PMC2644934

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Source receipt: pubmed, retrieved 7 Sept 2026.

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