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Article

The coupling of a trkB tyrosine residue to LTP.

Trends in neurosciences - 1 Apr 2003

Ernfors Patrik, Bramham Clive R

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) and its receptor, trkB, activate cAMP-response-element-binding protein (CREB) and the transcription of genes that is crucial for long-term potentiation (LTP). Any of several signaling pathways activated by trkB could be required for LTP. A recent study using mice carrying a mutation in a specific tyrosine residue of trkB pinpoints a necessary role for the...

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Share to Brain-Derived Neurotrophic Factor
Share to Cyclic AMP Response Element-Binding Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phospholipase C gamma

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Source

Identifiers

PMID: 12689763
DOI: 10.1016/S0166-2236(03)00064-X

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The coupling of a trkB tyrosine residue to LTP.PMID 12689763Read ↗

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