Article
Shc-binding site in the TrkB receptor is not required for hippocampal long-term potentiation.
Neuropharmacology - 3 Mar 2000
Korte M, Minichiello L, Klein R, Bonhoeffer T
Abstract excerpt
Recent evidence shows that neurotrophins are not only involved in neuronal survival and differentiation but also in modulating synaptic strength in the developing and adult nervous system. To understand how neurotrophins induce changes in synaptic strength, we have investigated signaling pathways downstream of the TrkB receptor, which binds brain-derived neurotrophic factor (BDNF) or NT-4/5. To test whether the...
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