Article
LAR protein tyrosine phosphatase receptor associates with TrkB and modulates neurotrophic signaling pathways.
Journal of neurobiology - 1 Nov 2006
Yang Tao, Massa Stephen M, Longo Frank M
Abstract excerpt
The identities of receptor protein tyrosine phosphatases (PTPs) that associate with Trk protein tyrosine kinase (PTK) receptors and modulate neurotrophic signaling are unknown. The leukocyte common antigen-related (LAR) receptor PTP is present in neurons expressing TrkB, and like TrkB is associated with caveolae and regulates survival and neurite outgrowth. We tested the hypothesis that LAR associates with TrkB...
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