Article
Incorporating individual error rate into association test of unmatched case-control design.
Human heredity - 1 Jan 2004
Hao Ke, Wang Xiaobin
Abstract excerpt
OBJECTIVES: Genotyping error commonly occurs and could reduce the power and bias statistical inference in genetics studies. In addition to genotypes, some automated biotechnologies also provide quality measurement of each individual genotype. We studied the relationship between the quality measurement and genotyping error rate. Furthermore, we propose two association tests incorporating the genotyping quality...
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