Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of differential genotyping error rate on the type I error probability of case-control studies.

Human heredity - 1 Jan 2006

Moskvina Valentina, Craddock Nick, Holmans Peter, Owen Michael J, O'Donovan Michael C

Abstract excerpt

OBJECTIVES: It is well known that genotyping error adversely affects the power of genetic case-control association studies but there is little research on its effects on type I error, and none that has addressed possible differences in genotype error rates between cases and controls. METHODS: We used simulations to examine the influence of genotyping error on the type I error probability given by case-control...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computer Simulation
Share to Data Interpretation, Statistical

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Haplotypes

Share to Linkage Disequilibrium

Share to Models, Genetic

Share to Models, Statistical

Share to Probability

Share to Reproducibility of Results

Source

Identifiers

PMID: 16612103
DOI: 10.1159/000092553

Genes

MAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of differential genotyping error rate on the type I error probability of case-control studies.PMID 16612103Read ↗

Impact of genotyping errors on the type I error rate and the power of haplotype-based association methods.Semantic proximity Read ↗

Assessing the impact of differential genotyping errors on rare variant tests of association.Semantic proximity Read ↗

Assessing the impact of non-differential genotyping errors on rare variant tests of association.Semantic proximity Read ↗

Allowing for genotyping error in analysis of unmatched case-control studies.Semantic proximity Read ↗

Quantifying bias due to allele misclassification in case-control studies of haplotypes.Semantic proximity Read ↗

A cost-effective statistical method to correct for differential genotype misclassification when performing case-control genetic association.Semantic proximity Read ↗

Incorporating individual error rate into association test of unmatched case-control design.Semantic proximity Read ↗

Quantification of the power of Hardy-Weinberg equilibrium testing to detect genotyping error.Semantic proximity Read ↗

Genotyping errors: causes, consequences and solutions.Semantic proximity Read ↗

Detection of genotyping errors and pseudo-SNPs via deviations from Hardy-Weinberg equilibrium.Semantic proximity Read ↗

How allele frequency and study design affect association test statistics with misrepresentation errors.Semantic proximity Read ↗

Genotyping errors and their impact on genetic analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.